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Infections that cause the malady include herpes simplex, ...
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A serious skin and mucous membrane ailment was termed Stevens - Johnson Syndrome after two pediatricians collaborated on a description of the rare disorder in 1922. It is treated as a medical emergency, usually demanding hospitalization to minimize complications. Treatment starts with eliminating the cause which likely is a severe reaction to a medication. It may also be caused by an infection, or an immune system disorder. Once the origin is determined, physicians focus on getting control of the symptoms.
The first signs may occur several days before the rash and include flu-like complaints of fever, sore throat, cough, and burning eyes. A person should seek medical attention immediately if unexplained skin pain is present, or a fast spreading red or purple rash appears, blisters of the skin or mucous membranes develop, skin sloughing occurs, or facial swelling exists.
Medications commonly linked to a diagnosis of Stevens-Johnson are anti-gout, non steroidal anti-inflammatory drugs, sulfonamides, penicillin and anticonvulsants. Infections that cause the malady include herpes simplex, herpes zoster, influenza, HIV, diphtheria, typhoid and hepatitis. Sometimes a physical stimulus such as ultraviolet light treatments or radiation therapy may be a trigger.
There are presently no standard treatments for this condition. Hospital support will replace fluids and nutrients in ones body. To sooth the rash or blisters, cool, wet compresses are applied. Gentle removal of dead skin may be necessary and topical anesthetic applied. The administration of pain medications, antihistamines, antibiotics or topical steroids may be indicated in the treatment of Stevens-Johnson Syndrome.
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